Is Trelegy And Breo The Same

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How Does Trelegy Ellipta Work

5. How to use inhalers – Ellipta (Incruse, Anoro, Relvar, Trelegy, Breo)

Trelegy Ellipta contains three active drugs.* Each works a little differently to manage symptoms of COPD and asthma:

  • Fluticasone reduces inflammation in your lungs and airways.
  • Umeclidinium reduces how much mucus is produced in your airways. It can also block muscle spasms in your airways.
  • Vilanterol works by relaxing muscles around your airways. This dilates your airways and makes it easier to breathe.

Overall, these drugs work together to reduce swelling and relax muscles in your airways. This should keep your airways open and relaxed so you can breathe more easily.

Talk with your doctor or pharmacist if you have more questions about how Trelegy Ellipta works.

* An active drug is an ingredient that makes a medication work.

Trelegy Ellipta And Breastfeeding

Its not known if Trelegy Ellipta is safe to take while breastfeeding. Theres no human data available on whether the active drugs in Trelegy Ellipta pass into breast milk or how the drug may affect a child. The three active drugs in Trelegy Ellipta are fluticasone, umeclidinium, and vilanterol.

In animal studies, umeclidinium was seen in the breast milk of mothers who were given the drug. However, this doesnt mean that Trelegy Ellipta will be present in human breast milk.

If youre breastfeeding, talk with your doctor before taking Trelegy Ellipta. They can advise you on the best way to feed your child.

Here are answers to some frequently asked questions about Trelegy Ellipta.

What Are The Possible Side Effects Of Trelegy Ellipta

The most common side effects include:1

  • Thrush in the mouth and throat
  • Runny nose and sore throat

The LABA medication in Trelegy Ellipta, vilanterol, may increase the risk of asthma-related death.1,3

If your breathing problems quickly worsen after taking Trelegy Ellipta, contact 9-1-1 right away.1

These are not all the possible side effects of Trelegy Ellipta. Talk to your doctor about what to expect or if you experience any changes that concern you during treatment with Trelegy Ellipta.

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Want To Learn More About Trelegy

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Once-daily TRELEGY is a prescription medicine used long term to treat COPD, including chronic bronchitis, emphysema, or both and to treat asthma in adults. TRELEGY 100/62.5/25 mcg is the only strength approved for COPD. TRELEGY is not used to relieve sudden breathing problems and wont replace a rescue inhaler.

Once-daily TRELEGY is a prescription medicine used long term to treat COPD, including chronic bronchitis, emphysema, or both and to treat asthma in adults. TRELEGY 100/62.5/25 mcg is the only strength approved for COPD. TRELEGY is not used to relieve sudden breathing problems and wont replace a rescue inhaler.

Once-daily TRELEGY is a prescription medicine used long term to treat COPD, including chronic bronchitis, emphysema, or both and to treat asthma in adults. TRELEGY 100/62.5/25 mcg is the only strength approved for COPD. TRELEGY is not used to relieve sudden breathing problems and wont replace a rescue inhaler.

Limitations of UseTRELEGY is not used to relieve sudden breathing problems and will not replace a rescue inhaler. TRELEGY should not be used in children younger than 18 years of age. It is not known if TRELEGY is safe and effective in children younger than 18 years of age.

  • TRELEGY contains vilanterol. Long-acting beta2-adrenergic agonist medicines such as vilanterol,

Is Trelegy Ellipta Similar To Alternative Drugs Such As Advair And Spiriva

Advair Vs. Breo Vs. Trelegy: What Is The Difference?

Yes. Trelegy Ellipta, Advair, and Spiriva are all inhalers used to manage COPD in adults. Trelegy Ellipta and Advair are also used to manage asthma in adults.

For more information about how Trelegy Ellipta compares to other drugs like Advair and Spiriva, talk with your doctor. They can tell you more about your treatment options to see if one of these drugs is right for you.

Yes, Trelegy Ellipta is used to manage chronic obstructive pulmonary disease symptoms in adults.

COPD refers to a group of lung diseases that make it harder to breathe. Its a progressive disease, which means symptoms gradually worsen over time. In addition to trouble breathing, you may have:

  • tightness in your chest
  • excess sputum production

Trelegy Ellipta is used long term to help keep your lung function from becoming worse. Youll use it every day to reduce COPD symptoms.

Some people with COPD experience exacerbations. These are sudden flare-ups of severe symptoms. COPD exacerbations often require treatment in the hospital. Using Trelegy Ellipta may help lower your risk of exacerbations.

Note: Trelegy Ellipta should not be used as a rescue inhaler for exacerbations or sudden breathing problems. While taking Trelegy Ellipta, continue to use your rescue inhaler as your doctor tells you to. If you have symptoms that feel life threatening, call 911 or get immediate medical help.

Asthma is a condition caused by swelling and narrowing of your airways and lungs. Symptoms can include:

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How Is Trelegy Ellipta Used

Your doctor will explain how you should use your Trelegy Ellipta inhaler. Theyll also explain how much to use and how often. Youll typically take one inhalation each day, at about the same time each day.

After each dose, you should rinse your mouth with water. This can help prevent thrush, a possible side effect of Trelegy Ellipta. Thrush is a fungal infection of the mouth and throat. Be sure to spit the water out instead of swallowing it.

To view step-by-step instructions for using Trelegy Ellipta, check out this site from the drugs manufacturer. You can also look at Trelegy Elliptas patient information sheet.

Note: Trelegy Ellipta should not be used as a rescue inhaler if you have sudden trouble breathing or a flare-up of symptoms. Its meant to be used every day, regardless of your symptoms. While using Trelegy Ellipta, continue to use your rescue inhaler as your doctor tells you to. If you have symptoms that feel life threatening, call 911 or get immediate medical help.

Trelegy Ellipta Use With Other Drugs

Trelegy Ellipta is approved for long-term treatment of chronic obstructive pulmonary disease and asthma. It should be taken every day to treat your condition over a long-term period.

Trelegy Ellipta contains three different drugs , so you usually wont need to take another maintenance medication along with it.

However, your doctor will likely want you to have a rescue inhaler in case you have sudden breathing problems.

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What Should I Know About Trelegy Ellipta Vs Breo Ellipta

Trelegy Ellipta and Breo Ellipta are both inhalers used to manage chronic obstructive pulmonary disease and asthma in adults.

Trelegy Ellipta contains three active drugs,* which are fluticasone, vilanterol, and umeclidinium. Breo Ellipta contains fluticasone and vilanterol. Different drug combinations may work better for COPD or asthma in some people.

For more information about how Trelegy Ellipta and Breo Ellipta compare, see this detailed comparison. Also, talk with your doctor about your treatment options to see if one of these drugs is right for you.

* An active drug is an ingredient that makes a medication work.

What Does Trelegy Ellipta Cost

How To Use Your Ellipta Inhaler

Costs of prescription drugs can vary depending on many factors. These include what your insurance plan covers and which pharmacy you use.

If you have questions about how to pay for your prescription, talk with your doctor or pharmacist. And you can visit the Trelegy Ellipta manufacturers website to see if they have support options.

You can also check out this article to learn more about saving money on prescriptions.

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Getting The Most Out Of Your Inhaler

Ask your doctor, pharmacist or asthma & respiratory educator to:

  • Explain how your inhaler should be used
  • Check you are using your inhaler properly
  • Tell you where to find the expiry date on your inhaler
  • Show you how to check if your inhaler is empty or nearly empty
  • Discuss any unwanted effects from your medication
  • Explain how to clean your inhaler.

Different brands of inhalers sometimes have slightly different instructions to each other for similar steps. The checklists in our How-To Video library have been simplified and standardised where possible to reduce confusion.

Your inhaler will come with instructions in the package. Always check the package insert for any specific instructions.

Trelegy Ellipta With A Rescue Inhaler

Trelegy Ellipta isnt approved to treat sudden trouble breathing. If you have sudden breathing problems, your doctor will likely want you to use a rescue inhaler.

Examples of rescue inhalers include albuterol and levalbuterol . You can use your rescue inhaler in between your doses of Trelegy Ellipta if you have flare-ups of COPD or asthma symptoms.

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Trelegy Ellipta And Breo Ellipta Drug Interactions

Trelegy Ellipta can interact with other medications. These include:

  • Anticholinergic tiotropium, ipratropium, or aclidinium
  • Long-acting beta agonists salmeterol, formoterol, arformoterol, olodaterol, or indacaterol
  • Other medications that contain steroids
  • Any medications taken to treat bacterial, viral, or fungal infections, including an HIV infection, such as ketoconazole, itraconazole, ritonavir, nelfinavir, or cobicistat

Breo Ellipta can interact with other medications. These include:

  • Other medicines that contain a LABA
  • Strong cytochrome P450 3A4 inhibitors, like ketoconazole
  • Monoamine oxidase inhibitors
  • Tricyclic antidepressants

Trelegy Ellipta and Breo Ellipta can interact with other medications. This can change how Trelegy Ellipta and Breo Ellipta and other medications work and can make side effects more likely. Tell your prescribing physician about all drugs youre taking, including vitamins and dietary supplements.

How Can I Help Prevent Thrush While Using Trelegy Ellipta

TRELEGY ELLIPTA

You can prevent thrush from developing by always rinsing your mouth after you take your dose of Trelegy Ellipta. And dont swallow the water that you rinse with. Thrush is a fungal infection that can occur due to the use of inhaled steroids such as fluticasone, one of the drugs in Trelegy Ellipta.

Symptoms of thrush include mouth pain or white patches in the mouth. If you develop symptoms of thrush, be sure to see your doctor. They can recommend medication to treat the current infection. Your doctor or pharmacist may also be able to recommend ways to help prevent a thrush infection from occurring in the future.

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Trelegy Ellipta For Copd

The Food and Drug Administration approves prescription drugs such as Trelegy Ellipta to treat certain conditions.

In addition to being FDA-approved to treat chronic obstructive pulmonary disease , Trelegy Ellipta is also FDA-approved to treat asthma. For more information, see the Trelegy Ellipta for asthma section below.

What To Do In Case You Use Too Much Trelegy Ellipta

Call your doctor if you think youve inhaled too much Trelegy Ellipta. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource. But if you have severe symptoms, immediately call 911 or your local emergency number. Or go to the nearest emergency room.

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Side Effects And Risks

Trelegy Ellipta and Breo Ellipta both contain fluticasone furoate and vilanterol. Trelegy Ellipta also contains umeclidinium. Therefore, these medications can cause some similar and some different side effects. Below are examples of these side effects.

Mild side effects

These lists contain examples of mild side effects that can occur with Trelegy Ellipta, with Breo Ellipta, or with both drugs .

  • Can occur with Trelegy Ellipta:

What If I Miss A Dose

How to Use an Ellipta Inhaler

If you miss a dose of Trelegy Ellipta, take it as soon as you remember. Dont take more than one dose in 24 hours. Never take two doses at once to try to make up for a missed dose.

To help make sure that you dont miss a dose, try setting a reminder on your phone. A medication timer may be useful, too.

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Accessible Medication Containers And Labels

If its hard for you to read the label on your prescription, tell your doctor or pharmacist. Certain pharmacies may provide medication labels that:

  • have large print
  • contain a code you can scan with a smartphone to change the text into audio

Your doctor or pharmacist may be able to recommend a pharmacy that offers these options if your current pharmacy doesnt.

Trelegy And Breo Studies

COPDTrelegy Ellipta and Breo Ellipta were both compared in a study evaluating over 10,000 patients being treated for COPD. In this study, called the IMPACT study, the main endpoint researchers were looking at was the annual rate of moderate to severe exacerbations in patients with COPD.

  • The results showed that Trelegy was more effective for reducing flare-ups and improving lung function compared to the two medicines in Breo. Trelegy reduced flare-ups by 15% compared to Breo over one-year, a significant effect.
  • The results also showed that patients who took Trelegy Ellipta could breathe out significantly more air in one second compared to those who took Breo Ellipta, which is known as the forced expiratory volume in one second . This improved lung function was sustained over the one year period.
  • Based on a survey, Trelegy also improved these patients health-related quality of life when compared to Breo, which included items such as daily symptoms, daily activities and perceived well-being.

AsthmaIn the CAPTAIN study in over 2,400 patients with asthma, Trelegy Ellipta led to an improvement in lung function when compared to Breo using two different strengths of Trelegy: 100/62.5/25 mcg and 200/ 62.5/25 mcg.

Your results can vary as each persons condition is unique. Your doctor can evaluate your symptoms and determine which treatment may be the best option for you.

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Common Side Effects Of Breztri Aerosphere And Trelegy Ellipta

The most common side effects of Breztri aerosphere in clinical trials include:

  • Upper respiratory tract infection, pneumonia
  • Back pain, muscle spasm

More serious side effects of Breztri aerosphere include:

  • Potential worsening of infections such as existing tuberculosis, fungal, bacterial, viral, or parasitic infections, ocular herpes simplex
  • Risk of impaired adrenal function
  • Hypercorticism and adrenal suppression
  • Glaucoma and cataracts, worsening of narrow-angle glaucoma
  • Worsening of urinary retention
  • Hypokalemia low levels of potassium may cause symptoms of muscle spasm, muscle weakness, or abnormal heart rhythm
  • Effects on your heart increased blood pressure, a fast or irregular heartbeat, chest pain
  • Serious allergic reactions rash, hives, swelling of your face, mouth, and tongue, breathing problems

The most common side effects of Trelegy Ellipta in clinical trials include:

  • Diarrhea, constipation
  • Painful and frequent urination
  • Fungal infections in your mouth and throat this is less likely if you rinse your mouth out with water after taking your Trelegy Ellipta
  • Increase in upper respiratory tract infections, like the common cold, the flu, and sinus infections
  • Changes in taste

More serious side effects of Trelegy Ellipta include:

Why Cant I Use Trelegy Ellipta If I Have A Milk Allergy

Breo Ellipta Information, Side Effects, Warnings and Recalls

Trelegy Ellipta contains lactose, which is a type of sugar in milk. Lactose is an inactive ingredient in Trelegy Ellipta that helps the medication reach your lungs.

So if you have a milk allergy, you may have an allergic reaction to the lactose in Trelegy Ellipta. These allergic reactions can be serious. There have been reports of severe allergic reactions occurring in people with milk protein allergies who took other powder medications with lactose in them.

If you have a milk allergy, talk with your doctor about safe treatments for your condition.

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When Is The Best Time To Take Trelegy

When is the best time to take trelegy? Bottom Line 1 You can take Trelegy Ellipta in the morning, afternoon or the evening, just be sure to take it at the same time each day. 2 If you miss your dose of Trelegy, take it as soon as you remember. Then, take your next dose at your usual time. 3 Always follow your doctors specific directions on how to use Trelegy Ellipta.

What to do if you miss a dose of trelegy? If you miss a dose of Trelegy, take it as soon as you remember. Take your next dose at your usual time. Do not take two doses at one time. If you take too much Trelegy Ellipta, call your doctor immediately or go to the nearest hospital emergency room right away if you have any unusual symptoms, such as:

How often can you take trelegy Ellipta at one time? Do not take more than one inhalation per day in a 24-hour period. If you miss your dose of Trelegy, take it as soon as you remember. Then, take your next dose at your usual time. Do not take two doses at one time. Always follow your doctors specific directions on how to use Trelegy Ellipta.

How often can you use a trelegy inhaler? Trelegy is only inhaled once per day because the medication effect lasts for at least 24 hours. Use your Trelegy Ellipta inhaler at the same time every day. How fast did Trelegy Ellipta work in studies?

Can I Use Trelegy Ellipta As A Rescue Inhaler

No, you should never use Trelegy Ellipta as a rescue inhaler. This is because it can take time for the medications in Trelegy Ellipta to begin working. If youre having sudden trouble breathing, your doctor will likely want you to use a rescue inhaler such as albuterol or levalbuterol .

If you have questions about how to treat sudden breathing problems while taking Trelegy Ellipta, talk with your doctor. They can discuss rescue inhaler options with you.

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Does Trelegy Ellipta Cause Weight Gain

No, Trelegy Ellipta doesnt cause weight gain. This wasnt reported in the drugs studies.

Weight gain can be caused by corticosteroids that you take orally . This type of drug is sometimes used to treat exacerbations of chronic obstructive pulmonary disease or asthma. This refers to times when symptoms suddenly get worse. Oral corticosteroids can cause weight gain, especially if theyre taken long term. One example of this type of drug is prednisone .

Trelegy Ellipta contains a corticosteroid that you inhale, called fluticasone. Unlike oral corticosteroids, fluticasone is not known to cause weight gain.

Keep in mind that having COPD or asthma can make it harder to be physically active. This can contribute to weight gain.

Talk with your doctor if youre concerned about your weight or weight gain. They can suggest ways to reach or maintain a weight thats healthy for you.

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